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Previcox for Dogs

By | Last Updated: 23rd February 2023

What is Previcox

Previcox is a non-steroidal anti-inflammatory drug (NSAID) used for pain, inflammation, and discomfort of joints caused by osteoarthritis in dogs [1, 3]. Available as flavored chewable tablets, it may as well be prescribed for relieving pain and inflammation following orthopedic and soft-tissue surgery [1, 2].

Can dogs safely take Previcox

Previcox is approved by the FDA for use in dogs and may be prescribed by vets as an anti-inflammatory and analgesic medicine [1, 2]. Studies have shown it to be effective and safe for dogs with osteoarthritis even after long-term use [4].

Quick Information

Previcox for Dogs

Generic name (active ingredients): Firocoxib [1]

Brand name: Previcox ® [1]

Type: Cyclooxygenase-inhibiting class, non-narcotic NSAID [2]

Who can take it: Dogs [2]

FDA approved: Yes [1]

Availability: Prescription medication [1]

Form: 57 mg, 227 mg chewable tablets [1, 3]

How does it work in dogs

The active ingredient firocoxib interferes with the functioning of the cyclooxygenase-2 (COX-2) enzyme, preventing the production of fatty acids known as prostaglandins, which are responsible for pain, inflammation, and fever [2, 3, 8]. However, it promotes the action of COX-1 enzyme, thereby helping in protecting the stomach lining, supporting kidney health, and promoting platelet production [3].

Previcox dosage: how much to give to dogs

Follow your veterinarian’s instructions regarding the dose, the normally prescribed dosage being 2.27 mg/lb (5.0 mg/kg) given once daily for osteoarthritis [1, 2]. For relieving postoperative pain and discomfort, it may be administered for 3 days [2]. Since these chewable tablets are scored with a groove, the pills may be split in half, preferably with food to reduce the risk of stomach upset [1].

Previcox starts working within a few hours of administering the initial dose [7].

If you have missed a dose, give it as early as possible but do not administer two doses at the same time.

Possible Side effects

While decreased appetite and vomiting are commonly experienced [1], look out for the following signs of drug intolerance that might as well occur due to Previcox overdose [1] in your dog:

  • Diarrhea (flatulence, an urgency to defecate) [1]
  • Increased water consumption and urination [1, 2]
  • Tarry stools [1]
  • Lethargy [2]
  • Incoordination (stepping oddly, taking large steps, body tremors, swaying of the torso) [1]
  • Behavioral changes (increased activity level, or aggression) [1]

Moreover, taking large amounts of Previcox may lead to complications like stiffening, jerking, drooling, muscle twitching (associated with seizure), and yellowing of the eyes, skin, and gums (associated with jaundice) [1] [2].

If your pet has had any of these symptoms, contact your vet immediately.

Contraindications: When not to give Previcox to your dog

Inform the vet about any pre-existing health issues in your dog. It is not prescribed to dogs that are:

  • Allergic to NSAIDs [1]
  • Pregnant or lactating [1]
  • Less than 7 months old or less than 12.5 lbs of weight [1]
  • Dehydrated, with kidney, liver, or heart disorders [1]
  • On a diuretic therapy

For avoiding possible drug interactions, Previcox should not be given to dogs under the following medications:

  • NSAIDs such as Meloxicam (Metacam), Deracoxib (Deramaxx), Etodolac (Etogesic), Carprofen (Rimadyl), or Aspirin [1]
  • Corticosteroids including prednisone, dexamethasone, triamcinolone, or cortisone [1]
  • Diuretics or ACE (Angiotensin Converting Enzyme) inhibitors [5]
  • Potentially nephrotoxic drugs [5]

Some vets [10, 11] have reported that Previcox can be given along with common allergy and pain medications including Benadryl and Tramadol.


    1. Firocoxib – Petmd.com
    2. Previcox Chewable Tablets – Drugs.com
    3. Previcox For Dogs – Petcarerx.com
    4. Long-term efficacy and safety of firocoxib in the treatment of dogs with osteoarthritis – Ncbi.nlm.nih.gov
    5. Previcox – Summary of Product Characteristics – Ema.europa.eu
    6. Previcox – 1800petmeds.com
    7. How PREVICOX (firocoxib) Works – Previcox.com
    8. Previcox Firocoxib – Ema.europa.eu
    9. Previcox® (Brand) – Drsfostersmith.com
    10. My dog is currently on Previcox, can I also give him Bendaryl – Justanswer.com
    11. Can I give my dog previcox and tramadol together – Justanswer.com

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