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By | Last Updated: 22nd February 2023

What is Deramaxx and how does it work for dogs

Deramaxx is a non-steroidal anti-inflammatory drug (NSAID), belonging to the coxib class of medicines, having no narcotic properties [3].

Being an NSAID, Deramaxx works by inhibiting the production of chemicals that cause any kind of inflammation [1]. It is a fast-acting drug, usually taking action within 24 hours of the first dose. Studies have shown it to be safe and effective for use in dogs.

Quick Information


Generic name: Deracoxib [3]

Brand names: Deramaxx

Is it approved by FDA: Yes [2]

Type: Oral non-steroidal anti-inflammatory drug (NSAID)

What is it used for: Treatment and management of osteoarthritis and postoperative pain [2, 3, 4]

Who can take it: Prescribed only for dogs. Never recommended for cats. Humans should not take it either [2]

Availability: Prescribed by veterinarians

Available forms: Chewable tablets [3]

Dosage: How much Deramaxx is safe for your dog

The dosage may vary depending on individual factors such as age, size, and weight of your dog, as well as the severity of the condition. Make sure to follow the prescribed dose.

Osteoarthritis usually affects the larger dog breeds. The most widely accepted dosage that veterinarians usually prescribe for inflammation and osteoarthritis-related pain is 0.45-0.91 mg/lb/day (1-2 mg/kg/day), given in a single dose per day [5].

For postoperative pain and inflammation in dogs that weigh less than or equal to 4 lbs (1.8 kg), vets usually prescribe 1.4-1.8 mg/lb/day (3-4 mg/kg/day) of Deramaxx in a single dose, and the duration of administration generally does not exceed 7 days [3].

Signs of Deramaxx overdose or toxicity

  • Lethargy and drowsiness
  • Lack of coordination [4]
  • Heavy or fast breathing
  • Seizures
  • Pale gums
  • Diarrhea
  • Vomiting [3]
  • Incoordination
  • Appetite loss
  • Dark, tarry stool

If you notice any of the side-effects or signs of overdose mentioned above, immediately contact your veterinarian or the Animal Poison Control Center Helpline (1-888-426-4435). Look out for any abnormal behavior in your dog while on the medication.

Deramaxx side effects in dogs [2]

It is usually considered a safe medication, with just mild, or no side effects reported in most cases. However, in some cases, it may cause:

  • Decrease or loss of appetite
  • Vomiting
  • Altered behavior
  • Diarrhea
  • Change in stool color
  • Yellowing of skin, white areas of the eye and gums (jaundice)
  • Sudden weight loss
  • Excessive thirst and changes in urine

Contraindications: When should you  not give Deramaxx to your dog

Dogs allergic to deracoxib, or other NSAIDs should not be given Deramaxx.

Taking NSAIDs always runs a risk of causing stomach ulcers in dogs. Inform your vet if your pet has any of the following underlying conditions:

  • A stomach or kidney condition [2]
  • Any condition that may already make the dog dehydrated
  • Pre-existing problems with appetite (anorexia) [5]
  • Problems such as bloody vomit or stools

Deramaxx should never be given along with aspirin or any other NSAIDs [3].


    1. Deramaxx – Drsfostersmith.com
    2. Deramaxx – Fda.gov
    3. Deramaxx – Drugs.com
    4. Deracoxib – Petmd.com
    5. Deramaxx Chewable Tablets – Drugs.com

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